Description from the NSA website about IME:
The Inline Media Encryptor (IME) is a government-developed media encryption device. It is positioned "in line" between the computer processor and hard drive to ensure that anything stored to the hard drive gets encrypted and anything retrieved from the hard drive gets decrypted. The IME protects data classified Top Secret and below. Data stored on the hard drive is considered unclassified when encrypted.
Nice. Read about the features. Certainly hardware based solutions are extremely useful. Wonder if there's a commercial device that conforms to similar standards available for public consumption. Hopefully not.